Active Trials
Working with researchers at Baylor Scott & White Health and institutions around the globe, our physicians, surgeons and advanced practice providers oversee a wide selection of clinical trials.
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Study Name: ENVISION
Study Title: ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation (ENVISION)
Sponsor: Abbott Medical Devices
PI: Harrington/Szerlip
Therapeutic Group: Aortic Valve
Study Name: ALLIANCE
Study Title: ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
Sponsor: Edwards Lifesciences
PI: Al-Azizi/Schaffer
Therapeutic Group: Aortic Valve
Study Name: Shockwave ILIT
Study Title: Intravascular Lithotripsy in High Risk Calcified Iliac Anatomy for Transfemoral TAVR (ILIT)
Sponsor: Baylor Research Institute
PI: Al-Azizi
Therapeutic Group: Aortic Valve
Study Name: ALIGN-AR
Study Title: The JenaValve ALIGN-AR Pivotal Trial (ALIGN-AR)
Sponsor: JenaValve Technology, Inc.
PI: Szerlip/Harrington
Therapeutic Group: Aortic Valve
Study Name: ICETEE
Study Title: Intracardiac Versus Transesophageal Echocardiographic Guidance for Left Atrial Appendage Occlusion (ICETEE)
Sponsor: Baylor Research Institute
PI: Al-Azizi
Therapeutic Group: Cardiology
Study Name: Shockify
Study Title: SHOCKWAVETM VS SURGICAL ENDARTERECTOMY OF CALCIFIED SEVERE COMMON FEMORAL ARTERY STENOSIS: COMPARISON OF EFFICACY, SAFETY, AND LONG-TERM OUTCOMES
Sponsor: Baylor Research Institute
PI: Sayfo
Therapeutic Group: Cardiology
Study Name: IMPROVE
Study Title: IMPact on Revascularization Outcomes of IVUS Guided Treatment of Complex Lesions and Economic Impact (IMPROVE)
Sponsor: MedStar Cardiovascular Research Network
PI: Al-Azizi
Therapeutic Group: Cardiology
Study Name: Symphony-PE
Study Title: SYMPHONY-PE Study for Treatment of Pulmonary Embolism
Sponsor: Imperative Care, Inc.
PI: Sayfo
Therapeutic Group: Cardiology
Study Name: SPYRAL AFFIRM
Study Title: SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
Sponsor: Medtronic Vascular
PI: Potluri
Therapeutic Group: Cardiology
Study Name: Ross (NARC)
Study Title: Prospective Long-Term Outcomes of a Standardized Ross Procedure (ROSS)
Sponsor: Baylor Research Institute
PI: Brinkman
Therapeutic Group: CV Surgery
Study Name: ROMA
Study Title: Randomization of Single vs Multiple Arterial Grafts (ROMA)
Sponsor: Weill Medical College of Cornell University
PI: DiMaio
Therapeutic Group: CV Surgery
Study Name: CTSN PACeS
Study Title: Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG (PACES)
Sponsor: Icahn School of Medicine at Mount Sinai
PI: DiMaio
Therapeutic Group: CV Surgery
Study Name: LeAAPS
Study Title: Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial (LeAAPS)
Sponsor: AtriCure, Inc.
PI: Hutcheson
Therapeutic Group: CV Surgery
Study Name: SmartPulse PAF
Study Title: A Study of the THERMOCOOL SMARTTOUCH Surround Flow (SF) Catheter With the TRUPULSE Generator for Treatment of Drug Refractory Symptomatic PAF (SMARTPULSE PAF)
Sponsor: Biosense Webster, Inc.
PI: DeVille
Therapeutic Group: Electrophysiology
Study Name: ODYSSEY-HCM
Study Title: A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy (ODYSSEY-HCM)
Sponsor: Bristol-Myers Squibb
PI: Afzal
Therapeutic Group: Heart Failure
Study Name: IMPACT
Study Title: IMpella-Protected cArdiaC Surgery Trial (IMPACT)
Sponsor: Abiomed Inc.
PI: George
Therapeutic Group: Heart Failure
Study Name: DISCOVER-HCM
Study Title: A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM) (DISCOVER-HCM)
Sponsor: Bristol-Myers Squibb
PI: Rawitscher
Therapeutic Group: Heart Failure
Study Name: ALLAY-HF
Study Title: Alleviant ALLAY-HF Study
Sponsor: Alleviant Medical, Inc.
PI: Szerlip
Therapeutic Group: Heart Failure
Study Name: CLASP IID/IIF
Study Title: Edwards PASCAL CLASP IID/ IIF Pivotal Clinical Trial (CLASP IID/IIF)
Sponsor: Edwards Lifesciences
PI: Smith/Szerlip
Therapeutic Group: Mitral Valve
Study Name: APOLLO
Study Title: Transcatheter Mitral Valve Replacement With the Medtronic IntrepidTM TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. (APOLLO)
Sponsor: Medtronic Cardiovascular
PI: Szerlip/Smith
Therapeutic Group: Mitral Valve
Study Name: PROSERA (GB002-3101)
Study Title: Efficacy and Safety of Seralutinib in Adult Subjects With PAH (PROSERA)
Sponsor: Gossamer Bio Inc. (GB002, Inc.)
PI: Bakshi
Therapeutic Group: Pulmonary Hypertension
Study Name: UNISUS
Study Title: Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension (UNISUS)
Sponsor: Actelion
PI: Bakshi
Therapeutic Group: Pulmonary Hypertension
Study Name: CLASP II TR
Study Title: Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial (CLASP II TR)
Sponsor: Edwards Lifesciences
PI: Szerlip/Smith
Therapeutic Group: Tricuspid Valve
Study Name: TRISCEND II Pivotal, CAS
Study Title: TRISCEND II Pivotal Trial
Sponsor: Edwards Lifesciences
PI: Smith/Szerlip
Therapeutic Group: Tricuspid Valve
Study Name: COVER DFUs I
Study Title: Multi-Center, Prospective, Randomized Controlled Trial Evaluating SkinTE® in the Treatment of the Wagner 2 DFUs (COVER DFUs)
Sponsor: PolarityTE
PI: Bastawros
Therapeutic Group: Vascular
Study Name: stAAAble
Study Title: Nectero EAST System Clinical Study (stAAAble)
Sponsor: Nectero Medical, Inc.
PI: Shutze
Therapeutic Group: Vascular
Study Name: Improve-AD
Study Title: IMPRoving Outcomes in Vascular DisEase–Aortic Dissection (IMPROVE-AD)
Sponsor: Duke University
PI: Gable
Therapeutic Group: Vascular
Study Name: ARISEII
Study Title: Evaluation of the GORE® Ascending Stent Graft (ARISEII)
Sponsor: W.L.Gore & Associates
PI: Brinkman
Therapeutic Group: Vascular
Study Name: TiGER
Study Title: Terumo Aortic Global Endovascular Registry (TiGER)
Sponsor: Vascutek Ltd.
PI: Gable
Therapeutic Group: Vascular
Explore our research initiatives
Driving the field of cardiovascular care forward
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