Active Trials
Working with researchers at Baylor Scott & White Health and institutions around the globe, our physicians, surgeons and advanced practice providers oversee a wide selection of clinical trials.
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Study Name: SOCIAL HF
Study Title: Seeking Objectivity in Allocation of Advanced Heart Failure (SOCIAL HF) Therapies Trial
Sponsor: Indiana University
PI: Gong
Therapeutic Group: Vascular
Study Name: SPIRARE II
Study Title: Selective Pulmonary-artery Intervention to Reduce Acute Right-heart tEnsion
Sponsor: Jupiter Endovascular
PI: Sayfo
Therapeutic Group: Vascular
Study Name: SELUTION4ISR
Study Title: SELUTION SLR™ 014 ISR: A Prospective Randomized Single Blind Multicenter Study to Assess the Safety and Effectiveness of the SELUTION SLR™ 014 Drug Eluting Balloon in the Treatment of Subjects With In-stent Restenosis
Sponsor: M.A. Med Alliance S.A.
PI: Stoler/Widmer
Therapeutic Group: Vascular
Study Name: Short-Cut
Study Title: Shockwave Lithoplasty Compared to Cutting Balloon Treatment in Calcified Coronary Disease – A Randomized Controlled Trial (Short-Cut)
Sponsor: Baim Institute for Clinical Reseach
PI: Potluri/Stoler
Therapeutic Group: Cardiology
Study Name: Shockify
Study Title: Shockwave™ Vs Surgical Endarterectomy Of Calcified Severe Common Femoral Artery Stenosis: Comparison Of Efficacy, Safety, And Long-Term Outcomes
Sponsor: CVRRC
PI: Sayfo
Therapeutic Group: Vascular
Study Name: VT Retrospective Registry
Study Title: Single center retrospective review of clinical outcomes after ventricular tachycardia catheter ablations
Sponsor: Foundation
PI: Rao
Therapeutic Group: Mitral Valve
Study Name: Trojan-C (Part B)
Study Title: Single-transcript sequencing of heart-transplant-related acute hepatitis C infection: A single-patient extension of TROJAN-C to gather pilot data in support of future NIH grant application
Sponsor: Baylor Scott & White Research Institute
PI: Gottlieb
Therapeutic Group: Aortic Valve
Study Name: SMART
Study Title: SMall Annuli Randomized To Evolut™ or SAPIEN™ Trial
Sponsor: Medtronic Cardiovascular
PI: Szerlip/Stoler
Therapeutic Group: Aortic Valve
Study Name: STLEUIS II
Study Title: Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
Sponsor: AliveCor, Inc.
PI: Widmer
Therapeutic Group: Vascular
Study Name: OHP-II Registry
Study Title: Sponsor-Initiated OCS Heart Perfusion (OHP-II) Registry
Sponsor: TransMedics
PI: Meyer
Therapeutic Group: Pulmonary Hypertension
Study Name: Roadster 3
Study Title: Srm–2022–01: Post-Approval Study Of Transcarotid Artery Revascularization In Standard Risk Patients With Significant Carotid Artery Disease
Sponsor: Silk Road Medical
PI: Foteh
Therapeutic Group: Cardiovascular Surgery
Study Name: SOLVE CRT
Study Title: Stimulation Of the Left Ventricular Endocardium for Cardiac Resynchronization Therapy in Non-responders, Previously Untreatable and High-risk Upgrade Patients
Sponsor: EBR Systems, Inc
PI: Kindsvater
Therapeutic Group: Heart Failure
Study Name: Storm-PE
Study Title: STORM-PE: A Prospective, Multicenter, Randomized Controlled Trial Evaluating Anticoagulation Alone vs Anticoagulation plus Mechanical Aspiration with the Indigo® Aspiration System for the Treatment of Intermediate High Risk Acute Pulmonary Embolism”,Penumbra
Sponsor: Inc. “
PI: Rosol
Therapeutic Group: Aortic Valve
Study Name: SUMMIT CS-04
Study Title: SUMMIT Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation
Sponsor: Abbott Medical Devices
PI: —
Therapeutic Group: Heart Failure
Study Name: SURTAVI
Study Title: Surgical Replacement and Transcatheter Aortic Valve Implantation (SURTAVI)
Sponsor: Medtronic Cardiovascular
PI: Brinkman/Stoler
Therapeutic Group: Heart Failure
Study Name: TECTONIC
Study Title: TECTONIC CAD Intravascular Lithotripsy (IVL) IDE Study
Sponsor: Abbott Medical Devices
PI: Sayfo/Stoler
Therapeutic Group: Cardiology
Study Name: Test to Treat
Study Title: Test to Treat: A Randomized Implementation Trial to Improve LDL-C Management after Hospitalization for Atherosclerotic Cardiovascular Disease ASCVD
Sponsor: Duke Clinical Research Institute
PI: Kulkarni
Therapeutic Group: Aortic Valve
Study Name: REDEFINE 3
Study Title: The cardiovascular safety of cagrilintide 2.4 mg s.c. in combination with semaglutide 2.4 mg s.c. (CagriSema 2.4 mg/2.4 mg s.c.) once-weekly in participants with obesity and established cardiovascular disease
Sponsor: Novo Nordisk A/S
PI: Hollander
Therapeutic Group: Heart Failure
Study Name: Conformal LAA
Study Title: The Conformal Early Feasibility Study – An Evaluation of the Safety and Performance of the Conformal Left Atrial Appendage Seal for the Left Atrial Appendage Occlusion (CONFORMAL EFS)
Sponsor: Conformal Medical
PI: Szerlip
Therapeutic Group: Cardiology
Study Name: LAAOS-4
Study Title: The Fourth Left Atrial Appendage Occlusion Study: (LAAOS-4)
Sponsor: Hailton Health Sciences Corporation
PI: Rao
Therapeutic Group: Electrophysiology
Study Name: MAGICAL SV
Study Title: The MAGICAL SV Trial – A Prospective, Multicenter, Randomized, Two-Arm, Single-blind Non Inferiority Trial to Evaluate the Safety and Efficacy of the MagicTouch™ Sirolimus-Coated Balloon in the Treatment of Small Vessels in Patients With Coronary Artery Disease.
Sponsor: Concept Medical Inc.
PI: Al-Azizi
Therapeutic Group: Vascular
Study Name: PROGRESS
Study Title: The PROGRESS Trial: A Prospective, Randomized, Controlled Trial to Assess the Management of Moderate Aortic Stenosis by Clinical Surveillance or Transcatheter Aortic Valve Replacement
Sponsor: Edwards Lifesciences
PI: Szerlip
Therapeutic Group: Vascular
Study Name: PACCS
Study Title: The Pulmonary Artery Catheter in Cardiogenic Shock (PACCS) Trial
Sponsor: Tufts Medical Center
PI: Guerrero Miranda/Hernandez-Montfort
Therapeutic Group: Aortic Valve
Study Name: AFFIRM
Study Title: The SPYRAL AFFIRM Global Clinical Study of Renal Denervation with the Symplicity Spyral Renal Denervation System in Subjects with Uncontrolled Hypertension
Sponsor: Medtronic Vascular
PI: Stoler/Potluri
Therapeutic Group: Cardiology
Study Name: TARGET IV
Study Title: The TARGET-IV NA Trial: Multicenter Randomized Assessment of the Firehawk® rapamycin TARGET eluting cobalt chromium coronary stent system – North American Trial
Sponsor: Medical Product Innovation (US Sponsor)
PI: Stoler
Therapeutic Group: Heart Failure
Study Name: Tribe-HF
Study Title: Therapy titration, Readmission reduction, and quality of life Improvement through Bloodless Estimation in Heart Failure patients (TRIBE-HF) II: Proof-of-concept study remote monitoring using the CardioID platform
Sponsor: General Prognostics
PI: Bindra
Therapeutic Group: Cardiology
Study Name: THOR IDE
Study Title: THOR: Prospective, single-arm, multicenter and open-label study is intended to evaluate the safety and efficacy of the Thor System in the treatment of de novo calcified lesions in native infrainguinal arteries in patients with peripheral artery disease (PAD).
Sponsor: Philips
PI: Sayfo
Therapeutic Group: Cardiology
Study Name: R2P OSPREY
Study Title: TIS2015-01: OSPREY ILIAC: Occlusive/Stenotic Peripheral artery REvascularization StudY for Common and/or External ILIAC Artery Using the Misago® RX Self-expanding Peripheral Stent
Sponsor: Terumo
PI: Sayfo
Therapeutic Group: Cardiology
Study Name: BICUSPID LOW RISK
Study Title: Transcatheter Aortic Valve Replacement (TAVR) with Medtronic TAVR System in Patients with Severe Bicuspid Aortic Valve Stenosis and at Low Predicted Risk of Mortality with Surgical Aortic Valve Replacement (SAVR)
Sponsor: Medtronic Cardiovascular
PI: Stoler
Therapeutic Group: Heart Failure
Study Name: Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients
Study Title: Transcatheter Aortic Valve Replacement With the Medtronic Transcatheter Aortic Valve Replacement System In Patients at Low Risk for Surgical Aortic Valve Replacement
Sponsor: Medtronic Cardiovascular
PI: Stoler
Therapeutic Group: Heart Failure
Study Name: APOLLO
Study Title: Transcatheter Mitral Valve Replacement with the Medtronic Intrepid TMVR System in patients with severe symptomatic mitral regurgitation – APOLLO Trial
Sponsor: Medtronic Cardiovascular
PI: Szerlip/Smith Ii
Therapeutic Group: Heart Failure
Study Name: TITAN:SvS
Study Title: Treatment In Thoracic Aortic Aneurysm: Surgery vs. Surveillance (TITAN:SvS)
Sponsor: Ottawa Heart Institute Research Corporation
PI: Brinkman
Therapeutic Group: Vascular
Study Name: TEAM-HF
Study Title: Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients with Advancing Heart Failure
Sponsor: Abbott Medical Devices
PI: Afzal/Guerrero Miranda/Hernandez-Montfort
Therapeutic Group: Electrophysiology
Study Name: Trifecta-Heart
Study Title: Trifecta-Heart cfDNA-MMDx Study:Comparing the dd-cfDNA Test to MMDx Microarray Test and Central HLA Antibody Test
Sponsor: Alberta Transplant Applied Genomics Centre
PI: Hall
Therapeutic Group: Tricuspid
Study Name: Triton-CM
Study Title: TRITON-CM: A Phase 3 Global, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Nucresiran in Patients with Transthyretin-Mediated Amyloidosis with Cardiomyopathy (ATTR amyloidosis with cardiomyopathy)
Sponsor: Alnylam
PI: Kale
Therapeutic Group: Pulmonary Hypertension
Study Name: Surfacer Postmarket Surveillance Study
Study Title: US Post-Market Surveillance Study of the Surfacer Inside-Out Access Catheter System (Surfacer System)
Sponsor: Merit Medical Systems, Inc.
PI: Vasquez
Therapeutic Group: Vascular
Study Name: Impella ECP
Study Title: Use of the Impella ECP in Patients Undergoing an Elective or Urgent High-Risk Percutaneous Coronary Intervention
Sponsor: Abiomed
PI: Potluri
Therapeutic Group: Cardiology
Study Name: VERITAS
Study Title: VERITAS: Prospective, single arm, multi-center, investigational study To evaluate the safety and effectiveness of the Amulet 2 device in patients who have non-valvular AF at increased risk for stroke and systemic embolism and who are suitable for short-term anticoagulation therapy.
Sponsor: Abbott Medical Devices
PI: Dohadwala/Eifling
Therapeutic Group: Heart Failure
Study Name: CHAMPION-AF
Study Title: WATCHMAN FLX versus NOAC for EMbolic ProtectION in the Management of Patients with Non-Valvular Atrial Fibrillation – CHAMPION-AF
Sponsor: Boston Scientific Corporation
PI: DeVille
Therapeutic Group: Heart Failure
Study Name: SPIRIT XLV PAS
Study Title: XIENCE Skypoint Large Vessel Post Approval Study
Sponsor: Abbott Medical Devices
PI: Potluri/Widmer
Therapeutic Group: Aortic Valve
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